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Women's Health Blog

By Tracee Cornforth, About.com Guide to Women's Health since 1997

Lexapro Side Effects

Wednesday April 19, 2006
Women's Health Forum: "My doctor recently put me on Lexapro for depression and anxiety. I noticed a lot of posts about weight gain and mood swings. Has anyone else noticed any other side effects from Lexapro?..."
Comments
April 25, 2006 at 3:25 pm
(1) Judy says:

I have actually lost weight on Lexapro but had gained with Zoloft, Prozac and Effexor. Yes, and I am more moody.

In addition to a low libido, does it just bother anyone to be touched, on the hand, the head. I find it annoying. I also seem to just do less – less exercise, less social functions. But that has always been with my antidepressants.

May 5, 2006 at 6:37 pm
(2) BOO says:

LISATX1 PRAYER JUST MADE MY BELLY JIGGLE, LAUGHING…KEEP THAT GREAT SENSE OF HUMOR..IT HELPS ESPECIALLY WHEN IT HURTS MOST. I WOULD RATHER LAUGH THAN CRY AND NO ANTIDEPRESSANT IS GOING TO BE PERFECT JUST LIKE THERE IS NO PERFECT CHURCH BUT LEXAPRO HAS HELPED ME A LOT..I AM ON 20 MG FOR ABOUT 2 YRS NOW AND CAN SAY IT WORKS BUT IS NOT A COMPLETE ANSWER..I HAVE TO PUT A LOT OF THINGS IN GOD’S HANDS AND REALIZE HE IS MORE ABLE THAN I TO DO THE IMPOSSIBLE SO WHEN LEXAPRO IS NOT CUTTING IT FOR ME, I CAN JUST RELAX!!!AND LEAVE IT TO HIM. I DO THANK GOD FOR GIVING SOMEONE THE ABILITY TO MAKE MANY MEDICATIONS WE DID NOT HAVE YEARS AGO.

January 19, 2007 at 2:55 am
(3) CC says:

I’ve been taking Lexapro for about a year and a half. It’s definately the best anti-depressant I’ve taken; however I have gained weight. Unfortunately it’s not perfect.

May 5, 2007 at 4:25 pm
(4) JT says:

I’d suggest you reseach about the MAJOR weight gain from Lexapro. I’ve never taken an antidepressant before and my doctor never mentioned this. I had been at the same weight for almost 13 years and upon beginning Lexapro 6 months ago, I gained a quick 12 lbs and couldn’t figure out why until I did some online research. I have stopped Lexapro, despite the side effects, as the weight gain has made me more depressed than when I started.

June 27, 2007 at 2:24 am
(5) Albertina Washington says:

I just started taking Lexapro, it caused my heartrate to increase and and increased in my blood pressure. I will not continue to take Lexapro because of these side effects.

July 14, 2007 at 3:49 pm
(6) tonya says:

I have been on Lexapro for 2 years. I have gained 50 pounds. I did not know why. From reading these comments, I am getting off of it for good.

November 26, 2007 at 3:01 pm
(7) Sheanean says:

I took lexapro for a whole 3 days. The first day was great. I was in a beautiful, happy place all day! Second day, not as good, but better than I had been. Feeling a little more distant and dragged down. Third day, I felt like I was completely seperated from the world and everyone I loved. I didn’t want to talk. By that evening, my head hurt so bad that I couldn’t even cry about it. All I could do was lay there quietly. I couldn’t talk. The next day, I was tired and my head still hurt. No more lexapro!

February 13, 2008 at 8:13 pm
(8) Andrea says:

I just started Lexapro. I was on Prozac 20mg. and swung right into lexapro 5 mg. When I took it, about 30 minutes later I couldn’t stop laughing. I laughed for at least 40 minutes. Today, I had a hang over and headache. Going back to Prozac.

April 11, 2008 at 8:11 pm
(9) Karimonster says:

Lexapro has worked WONDERS for my depression and anxiety. I’ve taken it for a month now. However, its not without side effects. The most troubling I’ve experienced is total Anorgasmia. At the same time, I’m not at all experiencing a decreased libido…I just can’t reach orgasm, which makes it exceptionally frustrating.

Has anyone who’s experienced this found their anorgasmia eventually resolving while they continue to take the medication? Or am I doomed?

September 19, 2008 at 7:56 am
(10) hmmmm says:

i’m surprised some of you have said you felt effects within a few days. the doctor and medication itself actually says it will take a minimum of 2 to 6 weeks to do anything! so perhaps the initial feelings you all had were psycological moreso.

the other thing to remember is that a side effect of lexapro is Anxiety…if you start off at too high a dose. so it can in fact make you worse (for those with panic anxiety)…so makesure your doc starts you off on a low dose first and then slowly build up to the higher dose. and don’t stop taking it even if you feel good! as you have to come off it slowly!

September 19, 2008 at 10:51 am
(11) malikah says:

We I have been taking Lexapro for about 2 weeks and I have lost 10 pounds. HoweverI just can’t reach orgasm, I will hvae to speak with my doctor about this!

November 18, 2008 at 2:05 pm
(12) Erika says:

I have been taking 10mg Lexapro for about 2.5 months now. I have noticed a change in my ability to sort out issues in my mind, and I have actually experienced an INCREASE in my libido. I have no trouble reaching orgasm, either. However, I have gained about 15-17 lbs (which on a small frame like mine is astronomical) and I’m not sure I can handle that side effect. I seem to eat EVERYTHING in my path!

I’m beginning talk therapy this week to try to get to the bottom of my ‘issues’. I think it will be what actually helps me the most.

December 18, 2008 at 9:11 pm
(13) Jt says:

I have been taking 10 mg of Lexapro for about 8 months now. My sex “drive” is fine – but I almost never climax anymore. Like others, I have gained about 10-15 lbs. due to eating everything I see. Now that I know this could be a side effect of Lexapro, I think I can better control my eating. Although I’m not quite sure how to tackle my orgasm situation…

February 11, 2009 at 6:00 pm
(14) Kellie says:

I have been on Lexapro for two weeks now and I have lost my appetite and feel tired alll the time,, I feel alot less anxiety and havent had any panic attacks( thank god ) But i seem to be more depressed. Cry alot more and feel really out of touch..

February 19, 2009 at 8:46 pm
(15) karea says:

hi i have been taking lexapro on and off for about two years. was wondering if anyone have been having problems with their teeth? have been having alot of toothaches since ive been on lexapro

February 23, 2009 at 3:59 pm
(16) shan says:

i’ve been taking lexapo 4 some time now and my biggest complaint is that i have memory loss from it… i gained about 10-15 pounds and my dr is now going to add welbutrin to it for the memory…

March 21, 2009 at 12:19 am
(17) Anonymous says:

I took Lexapro for 3 years after my only child moved out (empty-nest syndrome). I was only planning to take it for the 8 months recommended but continued taking it because once I had missed a pill and I had a major anxiety attack. I was afraid I couldn’t stop taking it. After months of wanting to stop I consulted my physician and was told I could start weaning myself off of it by taking my pill every other day for a month or so, than every 3rd day and so on. I took the pill every other day for 2.5 months and finally stopped cold turkey a week ago.

I haven’t noticed adverse side effects but have noticed I think clearly and don’t feel spacey or like I’m in a fog anymore. I didn’t realize the effect it was having on me after all this time until finally getting off of it. I have experienced a considerable amount of memory loss…prior to Lexapro I was told I had the memory of an elephant. I am not sure but hope my ability to remember things comes back soon.

I feel quite well, taking vitamins and eating healthy. I notice I’m not as tired as I while taking it and don’t feel so ‘lost’.

I would not advise anyone stopping their medication without strict guidance from the prescribing physician.

I hope this helps someone considering stopping taking the medication.

May 10, 2009 at 2:20 am
(18) Lee says:

Pardon me a guy leaving the note on the women’s forum but did want to share my view. My wife encouraged me to get medicine as she wisely knew I was depressed. Took Lexapro and within two days began to develop a sense of feeling like a zombie. I would stand in the kitchen and stare knowing in my head I had to do things but could not get my body to engage with my mind. I also developed extremely painful abdominal cramping and loose stool. Now you women are kind of use to the whole abdominal cramping thing… but not me! I could not take those two main side effects and took myself off after only 5 days. It took me three more days for the GI tract to resolve and the abdominal pain to diminish.

Ah, didn’t tell my wife I took myself off and when I did she laid into me, well… strongly encouraged me I mean to call my doctor for different med. Got on Prozac for three days now and have zero negative side effects thus far.

We are all different chemically so keep testing and find what works well for YOU! Even if Prozac works for me, it may be terrible for you. Take care of yourself and don’t give up.

May 30, 2009 at 6:21 pm
(19) Elizabeth says:

Why would women be used to abdominal cramping? I assume you are talking about stomach cramping which is not the same as the occasional menstrual cramping some women experience.

June 5, 2009 at 9:00 am
(20) NG says:

Have been on it for 18 months. First few weeks were horrible. i had every side effect possible. I nearly quit every day for a month! I still don’t take the full 10mgs cos it made me spaced out and forgetful. I take 5mg one day and 7.5mg the next. I have lost 4kg. I have not had a major anxiety/depression lapse in about a year. Though libido and orgasm is compromised. I recommend sticking through the first few weeks. Taper on slowly if you have to and take the lowest effective dose. I don’t think it’s a one size dose fits all kind of med. Good luck!

June 24, 2009 at 2:52 am
(21) EK says:

I just started taking Lexapro 10 mg 2 weeks ago. The doc said it would take 2-6 weeks for the medicine to get in my system, but within the first few days I noticed a difference. I wasnt as jittery and was actually calm for once. HOWEVER I went on a MAJOR eating frenzy and have been eating everything in sight. In just 3 weeks, I gained 15 pounds. That is NOT normal!. Also, this medicine keeps me from sleeping. I am going to talk to the doctor and get off this medicine! I wouldnt recommend this medicine to people who are self conscious about their weight

July 6, 2009 at 1:48 am
(22) Emma says:

I’ve been taking Lexapro for about a month and a half now. I actually didn’t have any side affects from the medication, and noticed it helped me after a few days, and i’m only on a 10mg dose. But I was wondering if it’s possible for the medication to affect my period cycles? I haven’t had one since I started the medication, and I know for sure there isn’t another reason for the absencse of it. anyone else have this problem?

July 11, 2009 at 11:38 pm
(23) britt says:

i have been on lexapro for 9 days now and i havent gone a day w/o debating weather to stay on it or not.i have had side effects everyday

the first few days were hell. ifelt like i had the flu i ached and i couldnt sleep.i had chills and a head ache

after a few days i felt a little better but i still cant sleep. every morning i get woke up from the small amount of sleep i get with stomach cramps and loose stool. i still debate stopping everyday but i am afraid to because of the withdraw side effects..

does anyone know if you can have withdraw after a week and a half on it?

August 1, 2009 at 6:33 pm
(24) marcia says:

i am quitting lexapro just after 6 days. I have never in my life been so sick and scared. I am not sure about withdraws but anything is better then the side effects i was getting. i am going to change my diet and try a more natural approach. F**K this to scare for me. I dont like being a zombie. I would never recomment Lexapro to anyone.

August 12, 2009 at 9:29 am
(25) Shelley Feller says:

I can’t believe some of these comments. I’ve been on Lexapro for 4 years. (20mg) Lexapro does not have the time to adhere to the neurons in your brain within a matter of hours or even days. I have not experienced negative effects. I realize that some people do, but NOT within the short time frames mentioned in this blog.

October 2, 2009 at 12:05 am
(26) Colee says:

I have been on lexapro for a month now. 10 mgs. It seems to be working very well for depression. I havent experienced any of the side affects except I feel shaky and nervousness. On the lexapro website, they say that weight gain is not a side affect. I have not gained weight on lexapro. I gained weight on prozac–20 lbs, ugh, that was horrible, I hated that. Paxil was good, no weight gain from that one. If I continue to feel shaky though, I’m going back to Paxil!

October 2, 2009 at 12:12 am
(27) Colee says:

And youre right shelly…its impossible to feel any antidepressant work in hours or even a few days. It takes any antidepressant between 1 to 4 weeks to work. Its not a “happy” pill and its not a muscle relaxant like valium, which does work immediately. Anti depressants dont work like that.

October 6, 2009 at 4:32 am
(28) Jill says:

I am sorry to disagree with you folks who think you cannot feel the effects of lexapro within hours or days. I took my first dose around 4pm yesterday and started feeling like sh*t around 8pm. I may have a hypersensitivity to this med because I have had almost every side effect mentioned and more. For one I have not been able to sleep yet and it’s almost 4:30 am. I had an incredibly scary anxiety attack worse than i ever have had in my life, i thought i was going to have a heart attack because my heart rate was racing so fast. I have been having nausea for hours and frequent urination followed by loose stool. I am also having a dry mouth and shakiness i can’t control. The scariest thing though seems to be a burning sensation at the stem of my neck and in my brain like every nerve ending in my brain has been supercharged. I cannot wait for this med to get out of my system because I feel crazy!!! I know people have different reactions, but thought i would share my story since I have been up all night. I am contacting my doctor as soon as the office opens!

October 29, 2009 at 10:15 am
(29) Lynn says:

I’ve been on Lexipro for 8 days now and have definitely experienced most of the side affects. Maybe it’s placebo affect, but I did feel much better the first few days. My mind wasn’t racing with what a “horrible person” I am, which was my major depression issue. Yesterday was the first day that I actually felt depressed again. But last night was also the first night I was able to sleep. The first 3 days I did experience bad headaches that went away with some Tylenol, but it was worth it not to be so sad. That subsided the 4th day. I’m still having the dizziness when I stand up. I haven’t tested out the libido or anorgasmia yet, we’ll see. Anyway, I’m definitely going to give it at least a few weeks to see if the side affects subside. If I start gaining weight like crazy, I’ll definitely quit. That would depress me for sure. Good luck everyone.

November 8, 2009 at 12:38 pm
(30) Donna says:

My neurologist put me on Lexapro 6 days ago because I suffer from chronic headaches. I am only on 5mg to start. Anyway, last night was one of the worst nights ever. My headache was so strong it woke me up and nothing I take makes it go away (motrin, tylenol). I am so frustrated. I know it takes time for the meds to work but am thinking about throwing in the towel. Not sure what else to do. Anyone else suffer headaches as a side effect of this drug? Did they go away after a week or two?

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