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Genital Herpes

Diagnosis, Treatments, Recurrent Episodes

By Tracee Cornforth, About.com

Updated: April 30, 2007

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

How is genital herpes diagnosed?

Although sores may be visible to the eye, several laboratory tests may be necessary to determine whether the sores are caused by HSV or another infection. The most reliable method of diagnosing genital herpes is by viral culture during which a new lesion is swabbed or scraped with the sample added to a laboratory culture that contains healthy cells. These cells are then examined, a day or two later, under a microscope that shows changes to the cells that indicate the growth of the herpes virus.

Other methods of diagnosing herpes are available to clinicians, however it's important to understand that the herpes virus is extremely hard to find and the fact that a clinician fails to detect the virus in an active sore does not mean that a person does not have genital herpes. Because of the difficulty diagnosing herpes clinicians may misdiagnose sores as something else such as ingrown hairs.

There is a blood test available that can detect antibodies to the virus, however this test cannot tell whether a person has an active genital herpes infection. The blood test can only determine whether a person has been previously infected by HSV and has produced antibodies to the virus. Although antibodies are present they do not protect a person from subsequent outbreaks of herpes. This blood test also cannot distinguish between oral or genital herpes. New blood tests which have the ability to distinguish between HSV type 1 and 2 are currently developed, however they are not available to the general physician population and are used mainly in research hospitals.

What are the treatments for genital herpes?

There are three drugs currently available to treat genital herpes. However, these medications are not cures. Pharmaceutical treatment of genital herpes may shorten the length of first episodes and reduce the severity and frequency of recurrent episodes. These drugs are:
  • Zoviraz® (acyclovir),

  • Famvir® (famciclovir),

  • and Valtrex® (valacyclovir).

Zoviraz is useful for first and recurrent episodes of herpes, while Famvir and Valtrex are approved by the FDA to treat recurrent episodes.

Patients can help speed healing and avoid spreading the infection by following a few simple steps during periods of active herpes:

  • Keep the infected area clean and dry.
  • Don't touch the sores; if you do wash your hands immediately.
  • Refrain from sex from the time you first notice symptoms until sores/lesions are completely healed and covered by new skin.

Recurrent episodes of herpes can be triggered by minor trauma, other infections including colds, menstruation, and stress.

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